Jaisalmer District is located in the great Indian Thar Desert, characterized by limited rainfall, poor groundwater resources, and challenging soil conditions for agriculture. Pearl millet is the major cereal crop of arid zone due to its adaptive features and ability to perform well with the use of limited inputs under harsh conditions. The existence of pearl millet in arid zone is important for maintaining crop diversity and long-term sustainability of agriculture, besides food and nutritional security to desert dwellers due to its climate resilience and nutritional superiority. The average productivity of pearl millet in district Jaisalmer is poor as compared to the state average i.e. 1030 kg/ha. Research reports revealed that with the adoption of high-yielding early maturing varieties along with recommended production technologies such as crop stand management with 1.33 lakh plants/ha, soil management, moisture management, balanced fertilizer application, life-saving irrigation at critical growth stages (tillering, flowering, and grain development stages), foliar application of agrochemicals 0.2% K2 SO4 + 100 ppm ascorbic acid or 0.2% K2 SO4 + 1000 ppm thiourea at grain development stage under moisture stress would be helpful in yield optimization of pearl millet in district Jaisalmer