The present paper reveals the valuable information on some ethno-veterinary plants, commonly used for treatment of diseases of domestic animals by the tribal people of Birbhum district, West Bengal. Altogether 25 plants were recorded which are used by the tribals in formulation of 17 different ethno-medicinal preparations for curing 14 different types of diseases. Many of these ethnoveterinary medicinal preparations are new, as they have not been recorded earlier in the standard literatures. Among the 17 ethno-medicinal uses, 11 are administered in the form of single drug curing indigestion, reduced lactation, colic pain, cold, fever, mouth disease, ear sore, eye problems etc. In 6 cases compound drug preparations are used in urinary troubles, diarrhoea, boils in nose etc. Lastly, the investigated taxa have been enumerated alphabetically with their botanical names and families, followed by tribal and local names, parts used, diseases and mode of administration.